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However, concomitant use of these drugs is known tramadol to increase the risk for seizures and serotonin syndrome (see the figure below) .
Tramadol works by changing the way the brain and body perceive tramadol pain .
Specifically, tramadol both inhibits serotonin and norepinephrine reuptake AND activates opiate receptors in the central nervous tramadol system to enhancing the inhibitory effects on pain transmission in the spinal cord .
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